THE CHALLENGE
The ICANS Monitoring Challenge
Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS) is one of the most serious complications of CAR-T therapy. Current monitoring often relies on symptoms becoming apparent, leaving limited opportunity for earlier intervention. As CAR-T adoption grows, clinicians need better tools to identify elevated risk and support proactive patient management.
Our Approach
Axvia AI is being developed as a clinical decision-support platform that combines patient characteristics, treatment factors, laboratory biomarkers, and clinical monitoring data to identify patients at elevated risk of ICANS.
The goal is to provide care teams with actionable risk insights that support earlier monitoring, informed decision-making, and improved patient safety.
Clinical Decision Worflow
A visual and descriptive breakdown of how our system operates from start to finish.
Data Acquisition
Clinical, laboratory, and treatment-related information is collected from routine care.
Risk Assessment
Axvia AI is being developed to analyze patient data and identify patterns associated with elevated ICANS risk.
Clinical Insights
Risk information is presented through an intuitive clinician-facing workflow.
Proactive Monitoring
Care teams can prioritize monitoring and intervention for higher-risk patients.
Need for Early Detection
As CAR-T adoption grows, the need for earlier ICANS risk detection becomes increasingly critical.
Up to 70%
Develop ICANS
34,000+
Global CAR-T Recipients
700+
Patients Treated in Canada
1 Mission
Earlier ICANS Detection
Current Stage
A detailed look at our current research milestones and clinical validation process.
Current Stage
Phase I
Axvia AI is currently in the product development and validation phase. The company is focused on refining the clinical workflow, validating assumptions through research and stakeholder engagement, and developing clinical prototypes.
Ready to partner with us in the next phase of oncology innovation?
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Founded through the McGill Dobson Centre for Entrepreneurship
axviaai.com